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Risk of Myocardial Ischemia and/or Infarction and Other Adverse Cardiac Events. The use of IMITREX injection is contraindicated in patients with CAD and those with Prinzmetal’s variant angina. Press and hold the autoinjector down against the skin I had a throbbing migraine headache today. Imitrex injections can be given by the user of the medicine or with assistance IMITREX Injection should only be used where a clear diagnosis of migraine or cluster headache has been established. I was out and didn't have my meds on me so this is the first thing I did when I got home. Place the autoinjector at a 90-degree angle at the skin injection site with the yellow needle guard gently pressed against the skin. However, perform a cardiac evaluation if these patients are at high cardiac risk. The prescriber should be aware that cluster headache patients often possess one or more predictive risk factors for coronary artery disease (CAD). Step by step instructions for self administering a Sumatriptan injection commonly occur after treatment with IMITREX injection and are usually non-cardiac in origin. Hold the autoinjector in one hand, and pull the red cap straight off. The goal of this medicine is to provide fast-acting relief in the treatment of oncoming or existing migraine headaches. Instruct patients on the proper use of IMITREX STATdose Pen and direct them to use injection sites with an adequate skin and subcutaneous thickness to accommodate the length of the needle Imitrex is a medicine that is used in the treatment of migraines. Recommended injection sites are the lateral portion of the thigh or deltoid area. The injection is intended to be given subcutaneously, and intramuscular or intravascular delivery must be avoided. This includes your doctors, nurses, pharmacists, and dentists. This medication can be found in pill, injection and nasal spray forms. Be sure to choose an area with a layer of fat. Avoid driving and doing other tasks or actions that call for you to be alert until you see how Imitrex (sumatriptan injection) affects you You’ll inject Imitrex under the skin of your outer thigh or the outer area of your upper arm. Your doctor or pharmacist will teach you how to. For all patients taking Imitrex (sumatriptan injection): Tell all of your health care providers that you take Imitrex (sumatriptan injection).